Make sure the pre-killed prey (such as a frozen mouse) is warmed up to at least room temperature before using it. Prey can be defrosted by floating it in cold water and then placing it in warm water just before feeding to your snake to thaw it.

Silky Terrier Dog Breed Playing Aro... Silky Terrier Dog Breed Playing Around

Why won’t my snake eat frozen mice?

Some pythons have no difficulty transitioning from live prey to frozen prey. Initially, some people find it difficult to eat food that has been defrosted. Snakes, whether young or old, will not allow themselves to go hungry, and will eventually consume a frozen mouse. A veterinarian must be consulted if a hatchling refuses to eat.